Spider-Woman is an animated television series, based on the Marvel Comics character Spider-Woman. The series was produced by DePatie-Freleng Enterprises and Marvel Comics Animation, and aired on September 22, 1979 to January 3, 1980, one season of sixteen episodes, on the ABC.

Jessica Drew, voiced by Joan Van Ark, is editor of Justice Magazine, a publication which has its own skyscraper and helicopter yet shows only two other employees — photographer Jeff and Jessica's teenage nephew Billy. When trouble rears its ugly head, Jessica comes up with an excuse to slip away and change into her Spider-Woman secret identity.

Spider-Man also guest stars in two episodes of the series.

The Spider-Woman cartoon should not be confused with Web Woman, a Filmation superheroine cartoon launched at around the same time, which reportedly prompted Marvel Comics into creating a Spider-Woman character to secure the copyright.

The cartoon differs considerably from the comic book in its premise and supporting cast, while modifying Spider-Woman's powers slightly.

Billy, Jeff, and Justice Magazine never appear in the comic book in any form. Nor do the darker elements of the comic book (the heavy use of Arthurian legend and the occult, Jessica's feelings of alienation) enter into the much brighter world of the cartoon.

The animated Spider-Woman retains the ability to fire bursts of energy from her hands called "venom blasts", but they are white instead of green and can apparently be used an unlimited number of times. Like Spider-Man, she has a "spider-sense": a kind of clairvoyance that allows her to see dangers as they happen, no matter where she is, she can close her eyes and see the event outlined by a spider-web. The animated Spider-Woman also has the ability to change into costume merely by spinning around, an idea borrowed from the Wonder Woman television series starring Lynda Carter.